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Integrin beta 2 anticorps

Cet anticorps anti-Integrin beta 2 est un anticorps Souris Monoclonal détectant Integrin beta 2 dans FACS, IF et Func. Adapté pour Humain.
N° du produit ABIN6937597

Aperçu rapide pour Integrin beta 2 anticorps (ABIN6937597)

Antigène

Voir toutes Integrin beta 2 (ITGB2) Anticorps
Integrin beta 2 (ITGB2)

Reactivité

  • 206
  • 59
  • 44
  • 9
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 110
  • 95
  • 43
  • 2
  • 1
  • 1
Souris

Clonalité

  • 163
  • 84
  • 2
Monoclonal

Conjugué

  • 103
  • 26
  • 24
  • 16
  • 10
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Integrin beta 2 est non-conjugé

Application

  • 154
  • 82
  • 61
  • 42
  • 42
  • 30
  • 29
  • 26
  • 26
  • 25
  • 18
  • 12
  • 10
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone

68-5A5
  • Specificité

    Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

    Réactivité croisée (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Stimulated human leukocytes

    Isotype

    IgG2a kappa
  • Indications d'application

    Known_Application: Functional Studies (Order Ab without Azide),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: Lymphocytes, granulocytes and macrophages in tonsil or lymph node.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    Integrin beta 2 (ITGB2)

    Autre désignation

    ITGB2

    Sujet

    Beta 2 (antigen CD18 (p95), CD18, Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement component 3 receptor 3 and 4 subunit, Complement receptor C3 beta subunit, Integrin beta-2 (ITGB2), LAD, LCAMB, Leukocyte Cell Adhesion Molecule CD18, Lymphocyte function associated antigen 1 (LFA1), MAC1, Macrophage antigen 1 (mac1) beta,CD18 / Integrin beta-2 (ITGB2)
    Cellular localisation: Cell Surface

    Poids moléculaire

    95kDa

    ID gène

    3689, 375957

    UniProt

    P05107

    Pathways

    Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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